Ozone Therapy in Retinitis Pigmentosa Patients: Clinical Evolution and Oxidative Stress Behavior in Retinitis Pigmentosa Patients Treated with Ozone Therapy over 20 Years

Abstract

Retinitis pigmentosa is characterized by bad night vision, decrease of visual field and/or acuity. The aim of this article is to assess ozone therapy's efficacy in these patients, treated twice a year over 20 years. Forty patients received ozone via the rectal way, during 20 sessions as the only treatment, with repetition of this cycle every 6 months, and 16 received other medical treatments (control group). A significant decrease of the visual field in the control group in respect to the ozone group was observed after 20 years of treatment. In the ozone group, 50% of patients improved their visual field, accompanied with homeostasis in redox state. It is recommended to apply ozone therapy at 6-month intervals in order to maintain visual capabilities. The opinions and conclusions expressed in this article are those of the authors and contributors, and do not necessarily reflect those of the International Ozone Association, the editors, Editorial Board, or Taylor & Francis. Readers are to make their own decisions with regard to the work presented. These medical articles are enclosed, as in the past, as a service to the members of the IOA interested in medical applications.