Abstract
Study objective To evaluate the influence of oxytocin on operative blood loss during laparoscopic myomectomy (LM). Design Prospective clinical study (Canadian Task Force classification I). Setting Tertiary care university hospital. Patients Sixty women scheduled for myomectomy because of symptomatic uterine myomas. Intervention Two ampules of oxytocin (10 u/mL/amp) were added to 1000 mL of saline solution running at the rate of 40 mU/min during the course of LM. Measurements and main results Blood loss and blood transfusion rate were significantly greater in the group without oxytocin infusion (group B) than in the group with oxytocin infusion (group A), with 445.0 ± 268.6 mL (95% CI 344.7–545.3) versus 269.5 ± 225.8 mL (95% CI 185.2–353.8)/(p <.05), and 36.7% versus 6.7% (p <.05), respectively. There was no significant difference in average age, body weight, or numbers of vaginal delivery and cesarean sections between the 2 groups. There was no significant difference in mean total myoma weight, main myoma size, postoperative stay, and complications between the 2 groups. Conclusion Oxytocin infusion combined with skillful surgical techniques may decrease operative blood loss and blood transfusion during LM.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
