Abstract
Oxytocin and social salience: a call for gene-environment interaction research
Highlights
The role of the neuropeptide oxytocin in social cognition and prosocial behavior continues to fascinate the scientific community (Bartz et al, 2011b)
Some of these discrepancies likely result from known issues in genetic association studies (e.g., Ioannidis et al, 2001; Lin et al, 2007), findings from studies of endogenous oxytocin (Strathearn et al, 2009), oxytocin administration, and oxytocin receptor (OXTR) (McQuaid et al, 2013) suggest that one method through which studies might yield more consistent findings is to include measures of environmental experiences in order to examine gene-environment interactions
In a study recently published in this journal, McQuaid et al (2013) examined how rs53576 genotype moderated the relationship between childhood maltreatment and depression symptoms in a racially/ethnically diverse sample
Summary
The role of the neuropeptide oxytocin in social cognition and prosocial behavior continues to fascinate the scientific community (Bartz et al, 2011b). Based on findings such as these, an increasing number of studies have begun to investigate how variation on the gene encoding for the oxytocin receptor (OXTR) may relate to socially relevant normative and pathological phenotypes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have