Abstract

Hypertensive structures of the hypothalamus were subjected to periodic electrical stimulation in unanesthetized, immobilized rabbits. After each period of stimulation, lasting 5 min and repeated at intervals of 5 min, the state of the mechanisms of oxygen transport (hemodynamics, affinity of hemoglobin for oxygen, oxygen capacity of the blood) was investigated. During the first two or three periods the oxygen consumption of the animals was increased, but later it fell because the function of the energy-dependent mechanisms of oxygen transport no longer corresponded to the requirements of the body. A decrease in the affinity of hemoglobin for oxygen under these conditions contributes to better deoxygenation of the blood in the tissues.

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