Abstract
Today, repair of congenital heart defects has become a routine operation with low mortality and morbidity in many subgroups of anomalies1. The knowledge that the ventricular myocardium continues to develop and conditions itself according to the loads present and that this mechanism can influence the long-term outcome in many cardiac anomalies, stress the operations towards infantile and neonatal age groups2,3. This, in turn, stresses the importance of the possible damage to the other organs and systems still developing at the time of cardiopulmonary bypass (CPB). While myocardial protection attempted by lowering the energy demands through topical cold and chemical cardioplegia1,4,5, the protection of other systems, including central nervous system (CNS), remains dependent on the oxygenation and the local wash out of metabolites by means of CPB.
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