Abstract

Abstract.Determinations of plasma and blood oxygen consumption during and after reticulocytosis due to repeated bleedings were performed on arterial blood samples taken from 9 rabbits. Plasma oxygen consumption showed no consistent relation to the degree of reticulocytosis. The oxygen consumption of whole blood followed promptly variations in the percentage of reticulocytes except for a decline in oxygen consumption often before the highest reticulocyte count was attained. This may be due to the fact that red cells, containing small remnants of the basophilic material, are counted as reticulocytes whereas the decline in oxygen consumption is probably related to the enzymatic deterioration of the citric acid cycle and the cytochrome system, which proceeds with considerable speed irrespective of the morphologic ripening of reticulocytes.

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