Abstract
Introduction Q10 seems to be one of the first scavenger systems acting against free radical insult and represents the coenzyme limiting the reduction of oxidated vitamin E. We previously observed lower Q10 serum levels in mothers and cord blood (CB) of term neonates born from elective cesarean section performed under general anaesthesia (CSG) compared to term neonates born from natural delivery (ND). General anaesthesia was performed using 50% oxygen (O2) and 50% N2O. Aim To assess the effect of maternal oxygen inhalation on neonatal antioxidant system we compared these results with Q10 serum levels obtained from mothers and cord blood samples of term neonates born from elective cesarean section performed under spinal anaesthesia without O2 administration (CSS). Methods We measured Q10 levels (mg/ml) by high pressure liquid chromatography in 15 mothers and cord blood samples of neonates born from CSS and we compared them to our previous data obtained from CSG and ND.
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