Abstract
Three at a time: Sequential carbonyl addition, chelation-controlled conjugate addition, and alkylation triggers the multicomponent assembly of diverse nitriles. The chelation-controlled conjugate addition–alkylation installs three new stereocenters (see scheme), thereby generating substituted nitriles that are ideal terpenoid precursors as illustrated in the synthesis of epi-dehydroabietic acid. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z52920_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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