Abstract

Continuous home oxygen therapy (HOT) is the therapeutic use of oxygen at higher concentrations than those found in ambient air for treating or preventing long-term manifestations of hypoxia, and has been shown to increase survival in patients with chronic obstructive pulmonary disease (COPD) and chronic respiratory failure (CRF). This concept has been extended by analogy to CRF originating from other respiratory and non-respiratory diseases, but its effectiveness has not been demonstrated. HOT has not been shown to be effective in improving the survival of patients with COPD and moderate hypoxemia, nor is there any consensus on its use during nocturnal desaturations in COPD and desaturations caused by exertion. In the current use of HOT, the patient's clinical and social situation should be assessed, oxygen supply sources must be adapted to the patient's mobility profile, the appropriate oxygen source must be selected for each patient, and oxygen therapy must be titrated to ensure that hypoxemia is corrected. Lines of research that will shape the future of HOT include investigating the ideal equipment, improving regulation systems and information about treatments, educating patients, and promoting research.

Full Text
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