Oxidiring updating of protein and endogenic intoxication as parameters of weight EPH-gestosis

Abstract

Is investigated contents of substances low and average molecular of weight (SLAMW) in plasma of blood, in erythrocytes and urine, and process of oxidizing updating serum s proteins of blood at 11 unpregnant women, at 22 pregnant women with physiological current of pregnancy, at 9 pregnant of risks group on development EPH-gestosis and at 33 pregnant, suffering by EPH-gestosis. On the basis of received facts following conclusions were made. Processes of agrgation of proteins prevail at physiological current of pregnancy. Endogenic intoxication at healthy pregnant not observed. In connection with an increase of concentration the active forms of an oxygen in a body of pregnant from risks group, process of agrgation of protein considerably more intensive. We can observe among the pregnant of risks group the first compensatory phase of endogenic intoxication, which accompanied by increase SLAMW in erythrocytes. The oxidizing updating of protein amplifies in a greater degree at pregnant women suffering by EPH- gestosis. Is observed as agrgation of proteins molecules, as its destruction.