Abstract

Oxidation of 5-amino-1,6-dimethyl-3-phenyluracil 1 by means of thallium(II) nitrate trihydrate in methanol gives 5,5-dihydroxy-1,6-dimethyl-3-phenyl-1,2,3,4,5,6-hexahydropyrimidine-2,4-dione 2, which is easily transformed into 1,5-dimethyl-4-hydroxy-5-methoxy-4-methoxycarbonyl-3-phenylimidazolin-2-one 3 by treatment with methanol.

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