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Abstract
In a few last decades oxidative stress detected in a variety of physiological processeswhere reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a central role. Theyare directly involved in oxidation of proteins, lipids and nucleic acids. In certain concentrationsthey are necessary for cell division, proliferation and apoptosis. Contractile muscle tissue at aerobicconditions form high ROS flow that may modulate a variety of cell functions, for exampleproliferation. However, slight increase in ROS level provide hormetic effect which may participatein adaptation to heavy weight training resulted in hypertrophy and proliferation of skeletal musclefibers. This review will discuss ROS types, sites of generation, strategies to increase forceproduction and achieve skeletal muscle hypertrophy
Highlights
In modern society, healthy people are often associate with sports lifestyle
Regular training provides a lot of benefits from enhancing immune system, metabolism and muscle force to normalizing blood pressure, body weight etc
reactive oxygen species (ROS) are chemically reactive molecules that formed as a natural byproduct of the normal metabolism of oxygen
Summary
Healthy people are often associate with sports lifestyle. Regular training provides a lot of benefits from enhancing immune system, metabolism and muscle force to normalizing blood pressure, body weight etc. No matter in what type of sport people are engaged their muscles always produce reactive oxygen species (ROS) in a greater or lesser extent. The reason for this lies in the mechanism of energy production. ROS are chemically reactive molecules that formed as a natural byproduct of the normal metabolism of oxygen In certain circumstances their levels may increase and significantly damage cell components. These ROS molecules act as oxidants leading to myoblast apoptosis or stimulators of proliferation to increase force and endurance of muscle fiber. Hormonal stimulation is an important part in increasing strength and endurance of skeletal muscle
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