Abstract
This study evaluated parameters of oxidative stress and antioxidant profile in fish after herbicide exposure. Cyprinus carpio were exposed to quinclorac (initial concentration 344.60μg/L) for 7, 30, and 90 days under rice field condition. Thiobarbituric acid-reactive substances (TBARS) were evaluated in brain, liver and muscle tissues, and protein carbonyl in liver. Enzymatic parameters such as catalase (CAT) and gluthatione S-transferase (GST) activities also were studied in liver. TBARS levels fluctuated in the brain showing increase in 7 days and decrease in 30 days, while in liver it was observed increase in 7 and 30 days, as well as in muscle after 30 and 90 days. The protein carbonyl was also increased after 30 and 90 days of herbicide exposure. CAT and GST activities were decreased after 30 and 90 days, respectively. The alterations observed suggest that a commercial formulation containing quinclorac causes oxidative damage in different tissues of carp after a long time of exposure. This study pointed out the importance of quinclorac toxicity considering the concentration used in rice fields.
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