OXIDATIVE STRESS CAUSED BY UV RADIATION AND THE USE OF FTIR METHOD TO STUDY ITS EFFECT ON THE BIOLOGICAL TISSUES

Abstract

Oxidative stress is caused by an imbalance between reactive oxygen species (ROS) generation and the capacity of antioxidant ROS scavenging systems and plays an essential role in the pathogenesis of many diseases. It is connected with cell damage, such as lipid peroxidation of membranes. One important source of oxidative stress is UV radiation, which can come from the natural environment or artificial sources like welding. While sources of artificial UV radiation emit specific wavelengths depending on the application, occupational exposure to natural UV radiation has a continuous spectrum from 290 nm to 400 nm. Oxidative stress can be measured by synchrotron radiation-based Fourier Transform Infrared (SR-FTIR) microspectroscopy. Oxidative effect of UV can be studied on human postoperative tissue. Here we show an in vitro study of the effect of UV C on the oxidative stress in human eye postoperative tissue.