Abstract

Oxidative Stress and Haemolytic Anaemia In Dogs and Cats: A Comparative Approach

Highlights

  • Red cells occupy a unique position within the vertebrate body

  • They are enucleated and lack cytoplasmic organelles [1]. They are unable to carry out ribosomal protein synthesis or mitochondrial oxidative phosphorylation. They are dependent upon glycolysis for whatever ATP supply is required to maintain their osmotic integrity, through various ion pumps, and for other energy requiring events, like synthesis of reduced glutathione, one of their main antioxidant defences [2, 3]

  • All vertebrate red cells have the main task of carriage of blood gases, oxygen from respiratory tissues and carbon dioxide from metabolically active tissues

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Summary

Review Article

Oxidative Stress and Haemolytic Anaemia In Dogs and Cats: A Comparative Approach. Gibson JS1*, Wadud R1, Lu DCY1, Brewin JN2 and Rees DC2 1Department of Veterinary Medicine, Madingley Road, Cambridge, UK 2Department of Paediatric Haematology, King’s College Hospital, London, UK. Received: October 15, 2019; Accepted: October 23, 2019; Published: October 31, 2019

Introduction
Dog and Cat Red Cells
Red Cell Metabolism
Osmotic fragility syndrome
Oxidative Challenge
Red Cell Antioxidant Defence
Findings
Increases levels of reduced glutathione and decreases haemolysis
Full Text
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