Abstract
The aim of the present study was to evaluate the indicators of oxidative stress (malondialdehyde [MDA]) and antioxidant status (ferric reducing ability of plasma [FRAP]; superoxide dismutase [SOD]; glutathione peroxidase [GSH-Px]; selenium [Se]; vitamin E) in dairy cows of the Slovak Pied cattle from 3 weeks before parturition to 9 weeks after parturition. The mean MDA concentration was significantly (P< 0.001) higher in the cows 1 week after calving compared to the cows 3, 6, and 9 weeks after calving. The lowest mean FRAP value was found in the cows 3 weeks after parturition. The SOD activities were increased during the whole monitored time (ANOVA,P< 0.001). A significant (P< 0.05) decrease of GSH-Px activities was recorded in the cows 1 week after calving compared to the weeks 6 and 9 after calving. Statistical multiple comparison test showed no significant changes in Se between the examined groups. The lowest mean vitamin E concentration was found in the first week after parturition. Significantly positive correlations (P< 0.05) were recorded between Se and vitamin E (r = 0.897), SOD and GSH-Px (r = 0.903), while Se and GSH-Px had no significantly positive correlation (r = 0.520). Significant changes between MDA and indicators of oxidative stress (SOD, GSH-Px, vitamin E) confirm that during parturition and onset of lactation, oxidative stress occurs in dairy cows. Exposure of peripartal cows to oxidative stress may cause an increased incidence of metabolic diseases.
Highlights
The aim of the present study was to evaluate the indicators of oxidative stress and antioxidant status in dairy cows of the Slovak Pied cattle from 3 weeks before parturition to 9 weeks after parturition
Pregnancy in dairy cows induces oxidative stress that can be a significant underlying factor leading to dysfunctional host immune and inflammatory responses that can increase the incidence and severity of infectious diseases (Sordillo 2013)
Dairy cows go through dramatic physiological changes to prepare themselves for the onset of lactation and the climb to peak milk production
Summary
The aim of the present study was to evaluate the indicators of oxidative stress (malondialdehyde [MDA]) and antioxidant status (ferric reducing ability of plasma [FRAP]; superoxide dismutase [SOD]; glutathione peroxidase [GSH-Px]; selenium [Se]; vitamin E) in dairy cows of the Slovak Pied cattle from 3 weeks before parturition to 9 weeks after parturition. Significant changes between MDA and indicators of oxidative stress (SOD, GSH-Px, vitamin E) confirm that during parturition and onset of lactation, oxidative stress occurs in dairy cows. Adequate trace mineral and vitamin nutrition during the peripartal period is essential for an effective antioxidant defence system It plays an important role in optimizing the immune responses and in helping the dairy cows to cope with the stress of early lactation The activities of main antioxidant enzymes (superoxide dismutase, glutathione peroxidase) and the ferric reducing ability of plasma concentration were determined, together with the concentrations of selenium and vitamin E
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