Abstract

THE blood fluke, Schistosoma mansoni, takes up large quantities of glucose and excretes lactic acid. It also uses oxygen but the role of this oxygen uptake in the metabolism of adult schistosomes is unclear. No increase in the rate of lactic acid excretion was observed when the worms were incubated under nitrogen and it was assumed that the flukes obtain all their energy by glycolysis1. Further studies suggested that there were only sufficient cytochromes present to account for 1/10 of the oxygen uptake of the worms2 and cyanine dyes inhibited 50% of the oxygen uptake without apparently adversely affecting them3.

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