Abstract
Background The kidneys are known as a target of hepatitis viruses. The renal impairment associated with hepatitis B virus (HBV) could be represented by lesions of glomeruli, or by injury of the renal tubules. Membranous nephropathy is the most common form of glomerulonephritis associated with HBV infection. We aimed to develop a prospective study that evaluated the relation between serum levels of 8-hydroxy-2-deoxiguanosine (8OHdG) and total antioxidant status (TAS) in patients with membranous glomerulopathy associated with HBV infection.
Highlights
The kidneys are known as a target of hepatitis viruses
Oxidative lesions of DNA in membranous glomerulonephritis associated with the infection with hepatitis B virus
We aimed to develop a prospective study that evaluated the relation between serum levels of 8-hydroxy-2-deoxiguanosine (8OHdG) and total antioxidant status (TAS) in patients with membranous glomerulopathy associated with hepatitis B virus (HBV) infection
Summary
The kidneys are known as a target of hepatitis viruses. The renal impairment associated with hepatitis B virus (HBV) could be represented by lesions of glomeruli, or by injury of the renal tubules. Membranous nephropathy is the most common form of glomerulonephritis associated with HBV infection. We aimed to develop a prospective study that evaluated the relation between serum levels of 8-hydroxy-2-deoxiguanosine (8OHdG) and total antioxidant status (TAS) in patients with membranous glomerulopathy associated with HBV infection
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