Abstract
Herein, we show that biradical character and appropriate distribution of spin density can be used for synthetic purposes. We demonstrate the rational domino annulation that includes dehydrative π-extension (DPEX) as the initiation step and subsequent oxidative electrocyclizations (EC) promoted by favorable localization of the unpaired electrons enabling up to four C-C bonds formed during the reaction. Contradicting to the Woodward-Hoffmann rules, the reaction proceeds at room temperature, whereas termination occurs when biradical character vanishes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
