Abstract

Oxidatively Generated Damage to Cellular DNA: Mechanistic Aspects.- Chlorination and Nitration of DNA and Nucleic Acid Components.- Prevention of the Mutagenicity and Cytotoxicity of Oxidized Purine Nucleotides.- Nucleotide Incision Repair: An Alternative and Ubiquitous Pathway to Handle Oxidative DNA Damage.- OGG1: From Structural Analysis to the Knockout Mouse.- Processing of 3?-End Modified DNA Strand Breaks Induced by Oxidative Damage.- Oxidative Damage and Promoter Function.- Oxidative DNA Damage and Telomere Shortening.- Oxidative Damage and Repair in the Mitochondrial Genome.- The Role of Oxidative Damage to Nucleic Acids in the Pathogenesis of Neurological Disease.- Nucleic Acid Oxidation and the Pathogenesis of Cardiovascular Diseases.- Oxidative DNA Damage and Carcinogenesis.- The Physiological and Pathological Roles of Oxidative Damage to DNA in Relation to Life Stage.- Analysis of 8-Hydroxy-2?-Deoxyguanosine as a Marker of Oxidatively Damaged DNA in Relation to Carcinogenesis and Aging.- Oxidatively Damaged DNA and Inflammation.- The Role of Antioxidants in the Prevention of Oxidative Damage to Nucleic Acids.

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