Oxidative Aromatization of 3,5-Disubstituted Isoxazolines to the Corresponding Isoxazoles with N,N,N’,N’-Tetrabromobenzene-1,3-disolfonamide (TBBDS) and 1,3-Dibromo-5,5-dimetylhydantoin (DBH) as Efficient Reagents under Mild Reaction Conditions

Abstract

The oxidation of 3,5-disubstituted isoxazolines to the corresponding isoxazoles has been carried out using N,N,N',N'-tetrabTomobenzene-1,3-disolphonamide and l,3-dibromo-5,5-dimethylhydantoin (DBH) as effective oxidizing agents under mild conditions at rt with good yields.