Oxidative Additions of Alkyl Halides to Palladium(0) Carbonyl Complex

Abstract

Abstract Oxidative addition reactions of alkyl halides to Pd(CO)(PPh3)3 were studied. Vinyl chloride, allyl chloride, allyl bromide, methallyl chloride, benzyl bromide, methyl iodide, and iodobenzene react with Pd(CO)(PPh3)3 to afford the corresponding acyl complexes of the type to the type trans-PdX(COR)(PPh3)2. The reactions proceed rapidly when the dissociation energy of carbon-halogen bond in the saturated alkyl halides is smaller than about 60 kcal/mol. In the case of the unsaturated alkyl halides the more inert carbon-halogen bond can be activated by initial formation of π complexes.