Oxidation Products of Nitric Oxide and the Concentrations of Antioxidant Vitamins in Parasitized Goats

S Dede,M Alkan,M Cemek,S Deger,T Kahraman,Y Deger

doi:10.2754/avb200271030341

Abstract

Oxidation Products of Nitric Oxide and the Concentrations of Antioxidant Vitamins in Parasitized Goats

Highlights

The status of nitric oxide oxidation products and antioxidant vitamins were investigated in goats infected with endoparasites and blood parasites (Trichostrongylidae sp. + Protostrongylidae sp. + Eimeria sp. + Babesia sp.), in this study
Nitrate concentrations of the infected group were higher than controls (p < 0.05) whereas vitamin E levels of the infected group were lower than the control group (p < 0.05)
The concentrations of the other indices examined were not statistically different between groups. These results suggest that the parasitic infections have direct effects on the concentrations of vitamin E, an important antioxidant, and on the increase of nitrate levels which may result from the pathophysiological effects of the parasitic infections

Summary

Introduction

The status of nitric oxide oxidation products and antioxidant vitamins were investigated in goats infected with endoparasites and blood parasites (Trichostrongylidae sp. + Protostrongylidae sp. + Eimeria sp. + Babesia sp.), in this study. The status of nitric oxide oxidation products and antioxidant vitamins were investigated in goats infected with endoparasites and blood parasites The concentrations of nitric oxide oxidation products (nitrate, nitrite) and antioxidant vitamins (vitamins E and C, β-carotene and retinol) were determined spectrophotometrically in the blood serum of all goats. The concentrations of the other indices examined were not statistically different between groups These results suggest that the parasitic infections have direct effects on the concentrations of vitamin E, an important antioxidant, and on the increase of nitrate levels which may result from the pathophysiological effects of the parasitic infections. Intra-erythrocytic parasites (Babesia, Plasmodium) metabolise Hb. As a result, the free O2 and H2O2 increase lipid peroxidation (Deger 1990; Ginsburg and Atamina 1994).

Methods

Results

Conclusion