Abstract
The oxidation of derivatives of 2-oxo-4-phenyl-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid with selenium dioxide was studied. It was observed that the 6-methyl group is oxidized to a hydroxymethyl, formyl, or carboxy group (in the latter case probably after dehydrogenation of the ring). The structure of the final product depends on the degree of substitution of the ring with respect to the nitrogen atom and on the substituent in the 5 position.
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