Abstract
AbstractThe oxidative degradation of glycylglycine (GlyGly) to formic acid, ammonium ion, and carbon dioxide occurs when it reacts with ferricyanide in acid medium, which has been studied spectrophotometrically at 303 nm at constant temperature. Kinetic runs have been performed under a pseudo-first-order condition of [GlyGly]0 >> [ferricyanide]0. The experimental rate law obtained for the redox reaction is: rate = ki [Fe(CN)63-] [GlyGly]x [H+]y[Pd(II)]0, where x and y are fractional orders. Effects of ionic strength and dielectric constant are also investigated. Activation parameters have been evaluated using Arrhenius and Eyring plots. A probable mechanism has been proposed and the derived rate law is consistent with the kinetic data.
Highlights
Peptides and proteins are the most important chemical compounds found in the living organism
This paper reports the kinetic study of oxidative degradation of glycylglycine (GlyGly) to formic acid, ammonium ion, and carbon dioxide by the ferricyanide complex
The results indicated that the reaction rate was not significantly affected by the catalyst (Table 1)
Summary
Peptides and proteins are the most important chemical compounds found in the living organism. This paper reports the kinetic study of oxidative degradation of glycylglycine (GlyGly) to formic acid, ammonium ion, and carbon dioxide by the ferricyanide complex. The oxidative behavior of the title dipeptide with the ferricyanide oxidant is investigated to explore the redox chemistry and to determine the activation parameters, which along with orders of the reactants are required for understanding the reaction mechanism These kinetic studies are sometimes helpful in the optimization of reaction parameters of organic syntheses, analytical conditions, and industrial production. In a related work by them, the oxidation kinetics of dipeptides such as ValGly, AlaGly, and GlyGly by Mn(III) have been studied in the presence of sulfate ions in acid medium at 299 K. We are reporting the oxidative behavior of this dipeptide using ferricyanide as the oxidant in perchloric acid solutions
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
