Abstract

Pulmonary oxalosis is a very rare pseudotumoral lesion; it is often secondary to an infection by Aspergillus niger and more rarely by A. flavus, A. fumigatus, A. luchurensis or by Beauveria bassiana. Here, we report two cases of chronic necrotizing pulmonary aspergillosis associated with oxalosis in two patients, a 17-years-old youth and a 69-years-old man with a history of tuberculosis. The diagnosis was based on histological examination of the surgical specimens highlighting the birefringent calcium oxalate crystals by polarization associated with branching septate hyphae. The culture yielded A. niger for the younger patient. Our aim is to discuss the diagnosis and the histogenesis of this pathologic association.

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