Abstract
IntroductionOxalate nephropathy has various etiologies and remains a rare cause of renal failure. To the best of our knowledge, we report the first case of oxalate nephropathy following octreotide therapy.Case presentationWe report the case of a 78-year-old Caucasian man taking chronic octreotide treatment for acromegaly who presented with acute oxalate nephropathy after antibiotic therapy. The diagnosis was confirmed by urinary analysis and a kidney biopsy. The recovery of renal function was favorable after hydration and withdrawal of octreotide therapy.ConclusionsOxalate nephropathy should be suspected in patients at risk who present with acute kidney injury after prolonged antibiotic treatment. This diagnosis should be distinguished from immuno-allergic interstitial nephritis and requires specific care. The evolution of this condition may be favorable if the pathology is identified correctly. Octreotide therapy should be considered a risk factor for enteric oxaluria.
Highlights
Oxalate nephropathy has various etiologies and remains a rare cause of renal failure
Oxalate nephropathy should be suspected in patients at risk who present with acute kidney injury after prolonged antibiotic treatment
Oxalate nephropathy is characterized by tubular deposition of calcium oxalate crystals due to either abnormal oxalate production or excretion
Summary
Diagnosis of oxalate nephropathy in susceptible patients and that octreotide should be considered a risk factor for enteric hyperoxaluria. Consent Written informed consent was obtained from the patient for publication of this manuscript and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Competing interests The authors declare that they have no competing interests. Author details 1Department of Internal Medicine, Divison of General Internal Medicine 4 rue Gabrielle-Perret-Gentil, 1211 Genève 4, Geneva, Switzerland. Author details 1Department of Internal Medicine, Divison of General Internal Medicine 4 rue Gabrielle-Perret-Gentil, 1211 Genève 4, Geneva, Switzerland. 2Department of Medical Specialties, Nephrology Division, Geneva, Switzerland. 3Service de Néphrologie et dialyse, Hôpital Tenon, APHP, Paris, France. 4Department of Pathology, Clinical Pathology Division, Hôpitaux Universitaires de Genève, Geneva, Switzerland
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
