Abstract

The results of induced ovulation regimens on 95 squirrel monkeys ( Saimiri sciureus) over a 7-year period are described. A distinct seasonal pattern of response was observed in the temperate climate. The pretreatment of squirrel monkeys with progesterone slightly suppresses the total number of follicles showing growth in response to the FSH but results in a significantly higher number of animals showing at least one ovulation. No significant differences were noted for ovarian response based on the length of time the animal had been in captivity. The effectiveness of the ovulation induction regimen over 20 or more consecutive courses of treatment was not significantly reduced, suggesting that antibodies were not formed against the gonadotropins.

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