Abstract
To report the first documented case of ovulation in a postmenopausal woman. Case study. University reproductive endocrinology and infertility clinic. A 57-year-old woman, who had been postmenopausal for 3 years and presented with breast tenderness and was found to have laboratory and ultrasound evidence of ovulation. Laboratory evaluation and transvaginal ultrasound. Ovulation in a postmenopausal woman. Laboratory evaluations revealed estrogen and progesterone consistent with an ovulatory pattern. Ultrasound revealed a thickened endometrium and a corpus luteum, both of which resolved after menses. This is the first report of ovulation in a postmenopausal woman. This observation opens the door to new questions about the sensitivity of the hypothalamic-pituitary-ovarian axis in menopause as well as about ovarian senescence.
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