Abstract
Favism is most common in those who have G6PD deficiency from the Mediterranean region. As hemolytic anaemia is the most common complication of G6PD deficiency, and it can be life-threatening in certain people. Infection, hyperglycemia, certain meals, and certain drugs can all cause hemolysis therefore, the most prevalent enzymopathy is glucose-6-phosphate dehydrogenase (G6PD) deficiency, which affects an estimated 400 million individuals, globally. Exposure to some medicines might cause hemolytic anaemia. The most important management technique is to avoid oxidative stresses by avoiding a hemolytic crisis. Also, avoidance of exposure to food and medicines that causes hemolytic anaemia episodes
 This review looks at etiology, epidemiology, pathopysiology, evaluation and management of the disease.
Highlights
Favism characterises a subgroup of patients with glucose-6-phosphate dehydrogenase (G6PD)deficiency's susceptibility to, and clinical presentation of, acute haemolytic crises as a result of eating broad beans
Avoidance of exposure to food and medicines that causes hemolytic anaemia episodes This review looks at etiology, epidemiology, pathopysiology, evaluation and management of the disease
Hemolytic anaemia is the most common complication of G6PD deficiency, and it can be life-threatening in certain people
Summary
Favism characterises a subgroup of patients with glucose-6-phosphate dehydrogenase (G6PD). Sickle cell disease (SCD) patients for example, frequently require transfusions of blood group antigennegative RBCs to avoid or respond to alloantibody formation; based on blood group antigen frequencies, they are more likely to receive RBCs from African-American donors, who may be G6PD deficient [3,4]. If these individuals have an infection or were given a drug that caused oxidative stress simulatenously , they would be at a greater risk Reduced haemoglobin and red blood cell counts, reticulocytosis, elevated lactate dehydrogenase, and increased unconjugated bilirubin are all relevant diagnostic results [1]
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