Abstract
Klebsiella pneumoniae is one of the most important human bacterial pathogens with an extensive range of community and hospital acquired infections that may lead to morbidity and mortality. Evaluating the prevalence and epidemic sources of infections and the pathogenicity mechanism of bacteria can be investigated by various typing methods. The emergence of multi-drug resistant strains and extended-spectrum s-lactamase (ESBL) producing isolates has already become a great challenge in nosocomial infection incidence. There are several reports on ESBL isolates of K. pneumoniae in Iran. However, our aim is a comprehensive analysis on ESBL isolates K. pneumoniae from different parts of Iran which has not yet been performed.
Highlights
Klebsiella pneumoniae is one of the most abundant species of the Klebsiella genus that causes complications such as urinary tract infections, Ventilator-Associated Pneumonia (VAP), sepsis and endophthalmitis in Asia and America
Emergence of multi-drug resistant strains has already become a great challenge in nosocomial infection incidence (Pokra et al, 2016; Kashani and Eliott, 2013)
The Klebsiella genus is classified among the five predominant common gram negative pathogens that could lead to nosocomial infections (Horan et al, 1988)
Summary
Klebsiella pneumoniae is one of the most abundant species of the Klebsiella genus that causes complications such as urinary tract infections, Ventilator-Associated Pneumonia (VAP), sepsis and endophthalmitis in Asia and America. The Klebsiella genus is classified among the five predominant common gram negative pathogens that could lead to nosocomial infections (Horan et al, 1988). More than 50% of these strains are isolated from wound, respiratory and urinary tract infections (Podschun and Ullmann, 1994). There are several reports on ESBL isolates of K. pneumoniae in Iran. A comprehensive analysis of ESBL isolates of K. pneumoniae from different parts of Iran has not yet been performed. The searches were done according to several English and Persian databases including PubMed, Scopus, Isi, Iranmedex and SID to identify studies addressing ESBL isolates of K. pneumoniae in Iran during the past decade
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