Abstract

AbstractThis chapter serves as an overview of the historical development of the methods for the analysis of interval-censored survival data. It begins with a description of how the interval-censored data arise from the studies where the subjects are followed periodically, and the time to the event of interest cannot be observed exactly. From a historical perspective, such data become more common with the emergence of new clinical and epidemiologic study designs. However, the well-developed methods that are used for right-censored survival data analysis could not be applied. This chapter follows on the methodological development of this area, starting in 1970 from a broad historical perspective.KeywordsClinical trialsInterval-censored dataNon-parametric estimationPeriodical follow-upSemiparametric analysis

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