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Abstract
Coronavirus infectious disease 2019 (COVID-19) first reported in Wuhan, China, causes serious respiratory illnesses such as lung failure and pneumonia. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) the pathogenic agent of COVID-19 has been confirmed as a novel coronavirus. WHO announced COVID-19 a global pandemic and now the whole world is eagerly waiting for vaccines and therapeutic treatment to get rid of this unstoppable coronavirus. As COVID-19 infection, a global threat creates unwanted human casualties and serious economic loss. To stop the ongoing uncontrolled situation researchers are racing to develop prevention and treatment strategies. Vaccines of different countries are in clinical and preclinical trials and the repurposed-drugs are providing to find out a positive result against COVID-19. The report is an analysis of published information focusing on treatment options including vaccination, drug-therapy, cytokines, therapeutic antibodies. Most of the vaccine’s development strategies and drugs target the surface structural spike glycoprotein or S-protein, the major inducer of pathogenic responses. Here, it is reviewed the features of SARS-CoV-2 and the global current status of therapeutic, and vaccine development for the prevention and effective treatment of COVID-19.
Highlights
Until the development of vaccines or discovery of any treatment option we cannot halt the new, deadly, and highly infectious coronavirus disease, COVID-19, which has brought much of the world to a locked-down situation and standstill [11]
In this review report authors would like to provide an overview of published different information about the Corona Virus Infectious Disease 2019 (COVID-19) which is a global threat
It is the prime concern to slow down the spread of the virus and reduce the rate and number of infections as early as possible by any means, in the meantime most effective and suitable prevention along with treatment options is being searched and trialed continuously
Summary
At the end of the year of 2019, another new coronavirus (Severe Acute Respiratory Syndrome Coronavirus-2) outbroke globally This SARS-CoV-2 causes respiratory-related illness was first reported in Wuhan, Hubei, China. This disease is officially called “the Corona Virus Disease 2019; COVID-19”. Health authorities in China reported to the World Health Organization (WHO) on 31 December 2019, a cluster of viral pneumonia cases of unknown cause responsible for respiratory infection in Wuhan, Hubei, and an investigation was started in early January 2020 [4]. Until the development of vaccines or discovery of any treatment option we cannot halt the new, deadly, and highly infectious coronavirus disease, COVID-19, which has brought much of the world to a locked-down situation and standstill [11]
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