Abstract
Objectives This study aimed to evaluate the immunoexpression of Twist and E-Cadherin in 59 lower lip squamous cell carcinomas (LLSCC) and to verify their relationship with clinical and histopathological parameters (tumor size, regional lymph node metastasis, clinical stage, outcome, recurrence and tumor histological grade. Possible correlations between these two proteins were also evaluated. Findings Higher expression of E-Cadherin was observed in LLSCCs classified in early clinical stages (stage I) (p Conclusion The results of this study suggest the potential involvement of Twist and E-Cadherin proteins in the modulation of events related to tumor progression and the poor prognosis of LLSCC.
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