Abstract
locoregional recurrence (LRR) rate was 44.6%. A total of 7 patients had LRR. Three patients had LRR in the H&N region only while 4 patients had LRR in both the H&N and esophageal regions. Univariate analysis determined that the radiation dose to H&N cancer (<70 Gy) and the occurrence of aspiration pneumonia were significant prognostic factors associated with OS (p Z 0.003 and 0.019, respectively). The occurrence rate of aspiration pneumonia was 58.3%. Alteration of the radiation dose to the swallowing organs, including the pharyngeal constrictor, glottic and supraglottic larynx, and proximal esophagus, was not sufficient to prevent aspiration pneumonia, but there was a slight correlative trend between the dose and aspiration. Conclusions: The presence of synchronous H&N and esophageal cancers is associated with poor patient outcome. The most important prognostic factor was the occurrence of aspiration pneumonia. Avoidance of aspiration after definitive CCRT may improve the treatment outcome of synchronous H&N and esophageal cancer. Author Disclosure: C.J. Hsu: None. W. Chun-Wei: None.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Radiation Oncology*Biology*Physics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
