Abstract
Overall hemostasis potential of blood plasma and its connection to molecular markers of the hemostasis system in patients with stenosis of coronary artery
Highlights
C urrently the most common cause of death in the world among non-communicable diseaseis ischеmiс heart disease, which in 2019 accounted for 16% of all deaths in the world
To determine the parameters of the hemostatic potential of blood plasma of each patients, turbidity curves of blood coagulation processes initiated by APTT reagent in the absence and presence of tissue plasminogen activator (t-PA) were obtained
The obtained data indicate that in 44.9 and 52.3% of patients with stenosis and angina, respectively, the formation and hydrolysis of the fibrin clot in blood plasma does not differ in shape from that observed in normal blood plasma of donors, Fig. 1, A and Fig. 2, А. 55.1% with stenosis and 47.7% of patients with angina have atypical forms of turbi
Summary
C urrently the most common cause of death in the world among non-communicable diseaseis ischеmiс heart disease, which in 2019 accounted for 16% of all deaths in the world. Since the half-life of the clot in plasma of patients with stenosis and angina did not differ, the concentration of plasmin formed in both cases should be the same, indicating the same rate of plasminogen activation in both clots.
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