Ovarian yolk sac tumor in a premenarchal girl

Abstract

Yolk sac tumors are highly malignant and commonly affect the ovaries, with amedian age of occurrence of 23years. We describe the case of an ovarian yolk sac tumor in a12-year-old premenarchal girl suffering from Hashimoto's thyroiditis and chronic spontaneous urticaria, which presented as arapidly growing solid cystic formation in the hypogastrium with an extreme increase in alpha fetoprotein (52,778 mg/ml). After ultrasound and MRI imaging, fertility-sparing staging surgery was performed, and the diagnosis of an ovarian yolk sac tumor with positive malignant cells in ascites was confirmed. The specificity of this case is the tumor classification into stage IC3 according to the FIGO and stageIII according to the Children's Oncology Group criteria. The postoperative course was complicated by apelvic abscess and asubcutaneous suture rejection reaction. Our case may incite further research on the relationship between autoimmunity and yolk sac tumors.