Ovarian superstimulation and intrauterine insemination for the treatment of unexplained infertility

Abstract

To evaluate the efficacy of controlled ovarian hyperstimulation (COH) and IUI in the treatment of unexplained infertility. The pregnancy rate (PR) in patients with unexplained infertility treated by COH and IUI (group A) was compared with a no-treatment control (group B). The Egyptian IVF-ET Center. Four hundred ninety-two patients with the diagnosis of unexplained infertility. Controlled ovarian hyperstimulation and IUI. Cycle fecundity per treatment cycle and PR per patient. In group A cycle fecundity was 20.1% per treatment cycle, and the PR was 34.7% per patient. In group B the PR was 8.9% per patient. Pregnancy rate per patient was significantly higher in group A when compared with the spontaneous PR in group B. Controlled ovarian hyperstimulation and IUI significantly increased the PR in patients with unexplained infertility when compared with a no-treatment control group.