Abstract
To evaluate the effects of laparoscopic ovarian drilling on hormonal profile and ovarian blood flow in women with polycystic ovaries. Prospective clinical trial. Sixty women with polycystic ovarian syndrome who failed to ovulate with clomiphene citrate and who subsequently underwent laparoscopic ovarian drilling were studied. Hormonal assay and ovarian blood flow measurement by colour Doppler ultrasonography were carried out before and after ovarian drilling. In the responder group in whom hormonal profiles improved, the Mean±SD pulsatility index and resistance index increased from 1.01±0.38 and 0.52±0.12 before operation to 2.18±0.45 and 0.75±0.15(P<0.001) after operation respectively. Peak cystolic velocity decreased from 14.39±6.7 before operation to 11.24±5.9(P<0.001) after operation. Laparoscopic ovarian cauterization in women with polycystic ovarian syndrome may result in a decrease in ovarian blood flow in parallel with decrease in serum levels of LH and androgen.
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