Ovarian size and response to laparoscopic ovarian electro-cauterization in polycystic ovarian disease

Abstract

Objectives: To evaluate endocrine and ovulatory changes in polycystic ovarian disease (PCOD) in relation to patients’ ovarian size. Methods: Three hundred and seventy-one women with clomiphene citrate-resistant PCOD underwent laparoscopic ovarian cauterization [type I or typical with ovarian volume >8 cm 3 or cross-sectional area >10 cm 2 ( n=211), type II with normal size ovary ( n=160)]. Serum levels of LH, FSH, DHEAS, PRL, and T before and 10 days after ovarian cautery, spontaneous and induced ovulation and pregnancy rates were compared. Results: Both groups responded to therapy in a similar manner, with a marked decrease in LH, FSH, DHEAS and T levels, with ovulation rates in type I 90.99%, type II 88.75% and pregnancy rates, 73.45% and 71.25%, respectively, with no statistical differences. Conclusions: Hormonal changes, ovulation and pregnancy rates were similar in the two types of PCOD, therefore it can be concluded that ovarian size is not a prognostic factor for response of PCOD patients to laparoscopic ovarian electro-cauterization.