Ovarian granulosa cell tumor – case report and literature review

Abstract

Gigantic (>10 cm) ovarian cysts are a rare finding in gynecology. In literature, there are only a few cases of giant ovarian cysts reported, mainly in older patients. Granulosa cell tumor (GCT) of the ovary is frequently a hormonally active, stromal cell neoplasm with the ability to produce sex steroids, such as estrogens. We report the case of a 61-year-old postmenopausal woman with a giant left ovarian cyst measuring 39 x 28 cm. The excision of the giant left ovarian cyst was performed, with intraoperative histologic examination; the result was granulosa cell tumor. We continued the surgery with a total abdominal hysterectomy and bilateral salpingo-oophorectomy and complete staging. On the final histopathological report the result was granulosa cell tumor of the ovary. The management of these high-risk ovarian tumors should have a strict follow up in order to avoid complications.