Abstract

Malignant germ cell ovarian tumors (MOGCTs) represent less than 20% of ovarian cancers. We conducted a retrospective study of 16 cases of (MOGCTs) diagnosed from January 2008 to December 2013. Results: During this time 26 cases of non epithelial ovarian malignancy were diagnosed which 16 are germinal tumors 61%. The age of patients ranged from 16 to 60 years. Abdominal mass was the principal symptom, it was present in 2/3 of cases (66%). All patients were surgically assessed with ovariectomy that was associated with hysterectomy in two patients. Chemotherapy was administered in 15 patients and BEP was the commonest regimen used. After a mean follow up of 25 months we obtained a clinical, biological and radiologic complete remission in 1/3 of cases, 3 recurrences , 2 deaths. Overall survival: After a median follow up of 25 months. We noted 2 death. The median OS was not reached. The 2-year OS rate was 93.8%. Event free survival (EFS): Events were defined as death, recurrence or progression of the disease. The median EFS was not reached.The 2-year EFS rate was 73%. Conclusion: (MOGCTs)are rare; they generally affect the young woman and are diagnosed at an early stage. Surgery has an important role.

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