Ovarian carcinosarcoma associated with mature cystic teratoma and tubal carcinoma - a case report

Abstract

Carcinosarcoma is a rare type of ovarian cancer of epithelial cell origin. The occurrence of carcinosarcoma associated with mature cystic teratoma is very rare. The recent information regarding histogenesis of pelvic or ovarian epithelial cancers suggests a tubal origin in most of these tumors. However, the presence of synchronous tubal neoplastic lesions and ovarian carcinosarcoma is extremely rare. We report a coexistence of ovarian carcinosarcoma and mature cystic teratoma with a synchronous tubal carcinoma. A 69-year-old woman presented with a pelvic mass. Intraoperatively, bilateral ovarian masses with peritoneal metastatic nodules were observed. Histologically, mature cystic teratoma was identified in both ovaries. The left ovary showed another component of carcinosarcoma. The left fallopian was macroscopically unremarkable but contained a microscopic area of high-grade serous adenocarcinoma in the distal part, with adjacent serous tubal intraepithelial carcinoma. While ovarian teratoma and carcinosarcoma may represent incidental coexisting lesions, the association between the ovarian carcinosarcoma and tubal carcinoma remains to be elucidated.