Abstract
Ovarian cancer is an important cause of mortality in women. The aim of this study was to evaluate the incidence and mortality rates and trends in the Iranian population and make predictions. National incidence from Iranian annual of National Cancer Registration report from 2003 to 2009 and National Death Statistics reported by the Ministry of Health and Medical Education from 1999 to 2004 were included in this study. A time series model (autoregressive) was used to predict the mortality for the years 2007, 2008, 2012 and 2013, with results expressed as annual mortality rates per 100,000. The general mortality rate of ovarian cancer slightly increased during the years under study from 0.01 to 0.75 and reaching plateau according to the prediction model. Mortality was higher for older age. The incidence also increased during the period of the study. Our study indicated remarkable increasing trends in ovarian cancer mortality and incidence. Therefore, attention to high risk groups and setting awareness programs for women are needed to reduce the associated burden in the future.
Highlights
Cancer is a major cause of morbidity and mortality, worldwide and the burden of cancer is globally increasing
Materials and Methods: National incidence from Iranian annual of National Cancer Registration report from 2003 to 2009 and National Death Statistics reported by the Ministry of Health and Medical Education from 1999 to 2004 were included in this study
The data for this study extracted from two sources; first, National death Statistic which reported by the Ministry of Health and Medical Education (MOH&ME) from 1999 to 2004 and published by MOH&ME) (Naghavi., 2002; 2003; 2004) stratified by age group, sex, and cause of death were included in this analysis to calculate the trend of mortality rate, the second source was national incidence data which derived from Iranian annual of National Cancer Registration report from 2003 to 2009
Summary
Cancer is a major cause of morbidity and mortality, worldwide and the burden of cancer is globally increasing. Ovarian cancer (OC) is the leading cause of death from gynecological cancer in western countries (Sant et al, 2003) and the fifth most common cause of cancer death in women worldwide (National cancer institute, 2005). This cancer is the number one cause of cancer death from all gynecological cancers worldwide (Jemal et al, 2011). Results: The general mortality rate of ovarian cancer slightly increased during the years under study from 0.01 to 0.75 and reaching plateau according to the prediction model. Attention to high risk groups and setting awareness programs for women are needed to reduce the associated burden in the future
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