Abstract

The financial burden of a cancer diagnosis is increasing rapidly with advances in cancer care. Simultaneously, more individuals are enrolling in high-deductible health plans (HDHPs) vs traditional insurance than ever before. To characterize the out-of-pocket costs (OOPCs) of cancer care for individuals in HDHPs vs traditional insurance plans. This retrospective cohort study used the administrative claims data of a single national insurer in the US for 134 826 patients aged 18 to 63 years with a new diagnosis of breast, colorectal, lung, or other cancer from 2008 to 2018 with 24 months or more of continuous enrollment. Propensity score matching was performed to create comparator groups based on the presence or absence of an incident cancer diagnosis. A new cancer diagnosis and enrollment in an HDHP vs a traditional health insurance plan. The primary outcome was OOPCs among individuals with breast, colon, lung, or all other types of cancer combined compared with those with no cancer diagnosis. A triple difference-in-differences analysis was performed to identify incremental OOPCs based on cancer diagnosis and enrollment in HDHPs vs traditional plans. After propensity score matching, 134 826 patients remained in each of the cancer (73 572 women [55%]; median age, 53 years [IQR, 46-58 years]; 110 071 non-Hispanic White individuals [82%]) and noncancer (66 619 women [49%]; median age, 53 years [IQR, 46-59 years]; 105 023 non-Hispanic White individuals [78%]) cohorts. Compared with baseline costs of medical care among individuals without cancer, a breast cancer diagnosis was associated with the highest incremental OOPC ($714.68; 95% CI, $664.91-$764.45), followed by lung ($475.51; 95% CI, $340.16-$610.86), colorectal ($361.41; 95% CI, $294.34-$428.48), and all other types of cancer combined ($90.51; 95% CI, $74.22-$106.79). Based on the triple difference-in-differences analysis, compared with patients without cancer enrolled in HDHPs, those with breast cancer paid $1683.36 in additional yearly OOPCs (95% CI, $1576.66-$1790.07), those with colorectal cancer paid $1420.06 more (95% CI, $1232.31-$1607.80), those with lung cancer paid $467.25 more (95% CI, $130.13-$804.37), and those with other types of cancer paid $550.87 more (95% CI, $514.75-$586.99). Patients with cancer and private insurance experienced sharp increases in OOPCs compared with those without cancer, which was amplified among those with HDHPs. These findings illustrate the degree to which HDHPs offer poorer protection than traditional insurance against unexpected health care expenses. Coupled with the increasing cost of cancer care, higher cost sharing in the form of increasing enrollment in HDHPs requires further research on the potential clinical consequences through delayed or foregone care.

Highlights

  • Cancer care expenses are increasing owing to advances in imaging, immunotherapy, and biologic pharmacotherapy in addition to improved prognosis, with a subsequent need for prolonged treatment and surveillance.[1,2] These welcome improvements in cancer care, have placed large financial burdens on some patients, with potential clinical consequences in the form of foregone or delayed care.[3]

  • Based on the triple difference-in-differences analysis, compared with patients without cancer enrolled in highdeductible health plan (HDHP), those with breast cancer paid $1683.36 in additional yearly out-of-pocket costs (OOPCs), those with colorectal cancer paid $1420.06 more, those with lung cancer paid $467.25 more, and those with other types of cancer paid $550.87 more

  • A total of 137 294 patients from the single national insurer data set with a diagnosis of breast (n = 17 751), colorectal (n = 5012), lung (n = 1922), or other types of cancer (n = 112 609) and 1 924 045 control individuals from the single national insurer data set with no cancer diagnosis met the inclusion criteria

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Summary

Introduction

Cancer care expenses are increasing owing to advances in imaging, immunotherapy, and biologic pharmacotherapy in addition to improved prognosis, with a subsequent need for prolonged treatment and surveillance.[1,2] These welcome improvements in cancer care, have placed large financial burdens on some patients, with potential clinical consequences in the form of foregone or delayed care.[3]. HDHPs sometimes reduce health care use and costs at the expense of necessary preventive services, including cancer screening procedures.[8,9] The combination of increasing cancer care expenses and cost-sharing plans may threaten to overwhelm the financial means of privately insured patients with a new cancer diagnosis

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