Outflow Vessel in the Plane of Main Vortex of Large Cerebral Aneurysms: A Study of Hemodynamic Analyses

Hao Li,Jing Wu,Ligang Chen,Tangming Peng,Changren Huang,Yong Jiang

doi:10.4236/nm.2015.62012

Abstract

Purpose: This study was designed to quantify and characterize the variations of hemodynamic parameters for those large cerebral aneurysms with outflow vessel in the plane of main vortex. Materials and Methods: A total of 19 consecutive patients with large cerebral aneurysms were constructed with the data of digital subtraction angiography. Those large cerebral aneurysms with outflow vessel in the plane of main vortex were included. Blood flow was hypothesized to be laminar and incompressible and blood Newtonian fluid. Computational fluid dynamics ICEM and Fluent software were used to simulate the computational hemodynamics of large cerebral aneurysms. Results: Hemodynamics parameters result of computational fluid dynamics showed that the velocity in the aneurysm neck, impact fields and the origin area of outflow vessels was obvious higher than that in the aneurysm sac and aneurysm dome. Wall shear stress was obvious higher in aneurysm neck, impact fields and the origin area of outflow vessels than that in the aneurysm sac and aneurysm dome. Conclusions: The location of outflow vessel played an impact on the level of blood flow within aneurysm sac for those large cerebral aneurysms with outflow vessel in the plane of main vortex.

Highlights

Hemodynamic status is regarded as one of the most significant factors responsible for the growth, development and rupture of cerebral aneurysms [1]
It is very important and essential for clinicians to master the hemodynamic status of aneurysms to evaluate and predict rupture risk, which is helpful in preoperative planning and preemptive treatments of cerebral aneurysms
After the blood flow entering into the aneurysm sac along the aneurysm wall, and the most obvious vortex was firstly formed

Summary

Introduction

Hemodynamic status is regarded as one of the most significant factors responsible for the growth, development and rupture of cerebral aneurysms [1]. Hemodynamic variables such as flowpattern, wall shear stress (WSS) and wall shear stress gradient (WSSG) have been hypothesized to be the causes of aneurysms [2] [3]. The previous published reports showed that the rupture risk of large aneurysm was higher than that of small aneurysms [4] [5] It is very important and essential for clinicians to master the hemodynamic status of aneurysms to evaluate and predict rupture risk, which is helpful in preoperative planning and preemptive treatments of cerebral aneurysms. In this study, using computational fluid dynamics (CFD) and angiographic image analysis, our objectives are to quantify and characterize the variations of hemodynamic parameters for those large cerebral aneurysms with outflow vessel in the plane of main vortex

Objectives

Methods

Results

Conclusion