Outcomes of Ureteroscopy vs Mini-Percutaneous Nephrolithotomy for Pediatric Upper Urinary Tract Calculi: Comparative Nonrandomized Outcomes from Two Tertiary Endourology Referral Centers.

Abstract

Introduction: Pediatric upper urinary tract calculi can be treated by ureteroscopy (URS) or mini-percutaneous nephrolithotomy (mPCNL). We wanted to compare outcomes of URS and mPCNL from two tertiary referral centers that specialized in one of these treatments for pediatric stone disease. Materials and Methods: Data were collected from two tertiary centers for a 10-year period (2010-2019); one center specializing in URS and the other in mPCNL for consecutive patients ≤16 years undergoing either of these minimally invasive interventions. Upper urinary tract stones included stones in the kidney, pelviureteral junction, and proximal ureter, whereas mid or distal ureteral stones were excluded. Data were collected on patient and stone demographics. Outcomes of interest included stone-free rate (SFR) and complication rates. Results: During the study period, 55 patients underwent URS (group 1) and 40 patients underwent mPCNL (group 2). The mean stone size for groups 1 and 2 were 11.4 and 14.5 mm, respectively, whereas twice as many patients in group 1 had multiple stones. The final SFR and complication rates for groups 1 and 2 were 100% and 97.5%, and 5.4% and 12.5%, respectively. Although there were two Clavien II and one Clavien IV complication in the URS group, all five complications in mPCNL group were Clavien I. Conclusions: Our study shows excellent outcomes for upper urinary tract stones with both URS and mPCNL. Although treatment choices should be tailored to patients, each modality carries different advantages and our results reflect that high-volume centers specializing in a particular technique offer best outcomes, and this must also be borne in mind when counseling patients.