Abstract
BackgroundBehçet's disease (BD) is an autoimmune condition that involves multiple systems. The most common arterial manifestation in BD patients is pseudoaneurysm, which has higher frequency than aneurysm formation.ObjectivesTo clarify the importance of profunda femoris artery in BD pseudoaneurysm, and present a new method for identifying healthy segments for anastomosis.MethodsFifteen patients presented at a vascular department with pseudoaneurysms of the common femoral (CFA) and superficial femoral artery (SFA), were diagnosed with BD and underwent surgical intervention at Kasr al Ainy hospitals over 2 years.ResultsAll patients were male. The patients ranged in age from 30 to 40 years (mean, 33.8±2.6 years). Mean duration of the disease was 5±3.4 years. Eight (53.3%) CFA graft interpositions, six (40%) mid SFA graft interpositions, and one (6.66) distal SFA graft interposition were performed. Eight (53.3%) of these operations were performed using Dacron graft and sartorius flap, three (20%) were performed with a polytetrafluoroethylene graft, and four (26.66) with a great saphenous vein graft. Two cases (13.33%) were accidentally discovered while four cases (26.66%) had short distance claudication, four cases (26.66%) had pain at rest, and five cases (33.33%) presented with pulsatile swelling correlated with pseudoaneurysm size (p = 0.005). Patients were followed-up over 1 year for new aneurysms and recurrence.ConclusionsSurgical repair with muscle flap coverage, with or without ligation of profunda femoris artery, does not affect prognosis. An alternative method for identifying healthy segments of femoral artery may be frozen section and examination of the artery to decrease the risk of recurrence at the site of anastomosis.
Highlights
Hulusi Behçet described Behçet’s disease (BD) as an autoimmune condition that involves multiple systems in 1937.1 Diagnostic features of the disease include recurrent oral ulcers, skin and eye involvement, and genital aphthosis
Vascular involvement occurs as true aneurysm or pseudoaneurysm formation in arteries, thrombotic occlusion in arteries, and thrombosis of veins.[4]
Pseudoaneurysms are more highly prone to rupture than aneurysms and can be a cause of death in BD patients, due to bleeding or ischemia.[6]
Summary
Hulusi Behçet described Behçet’s disease (BD) as an autoimmune condition that involves multiple systems in 1937.1 Diagnostic features of the disease include recurrent oral ulcers, skin and eye involvement, and genital aphthosis It can affect variable sized segments of both arterial and venous vessels.[2] Arterial involvement occurs in about 2.2-18% of patients, with a mostly male population.[3] Vascular involvement occurs as true aneurysm or pseudoaneurysm formation in arteries, thrombotic occlusion in arteries, and thrombosis of veins.[4] Pseudoaneurysms are seen with a notably higher frequency than true aneurysms in BD patients.[5]. All patients were followed-up regularly at 3-month intervals They were examined in the outpatients clinic for graft patency and formation of new false aneurysms, bleeding, or infection and, in case of suspicion, a further examination was performed, usually CTA. P values less than 0.05 were considered statistically significant
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
