OUTCOMES OF PATIENTS WITH ST SEGMENT ELEVATION MYOCARDIAL INFARCTION AND LEFT VENTRICULAR HYPERTROPHY: 25-YEAR POPULATION-BASED STUDY

Abstract

Objective: Left ventricular hypertrophy is a common finding in hypertensive patients. The increase in myocardial masse is accompanied with an elevation of oxygen demand. The occlusion of a coronary artery in ST-segment elevation myocardial infarction (STEMI) leaves the myocardium without oxygen supply. This depletion is harmful to myocardial cells and its effect could be more important in left ventricular hypertrophy patients. Aim: To evaluate the effect of left ventricular hypertrophy on Stemi outcomes. Design and method: Patients with STEMI underwent an echocardiographic exam within two days from the event and left ventricular hypertrophy (LVH) was evaluated using the left ventricular mass calculated using echocardiography. The primary endpoints were in-hospital and 1-year cardiovascular events. The secondary endpoints were left ventricular ejection fraction. Results: In total, 1605 patients were admitted for STEMI. There were 489 hypertensive patients. 28% had LVH. There was no difference in risk-adjusted in-hospital mortality between patients with and without LVH (p = 0,149). Both groups showed the same risks of developing life threatening arrythmias (p = 0,287). Left ventricular ejection fraction was evaluated in both groups. Patients with LVH did not have more risk of systolic dysfunction than the other group of patients (p = 0,098). Conclusions: Patients with left ventricular hypertrophy undergoing STEMI had similar outcomes compared to patients without LVH.