Abstract
In patients with favorable wound healing profiles and surgical defects in well-perfused locations, second intention wound healing often leads to excellent cosmetic results after Mohs micrographic surgery. Second intention healing can be modified and accelerated with the use of acellular wound matrices, serving as a foundation to facilitate re-epithelialization and formation of granulation tissue.
Highlights
Second intention healing occurs when a surgical defect is allowed to heal by natural granulation and re-epithelialization rather than closed by a planned reconstructive technique
As granulation tissue forms and an open wound contracts, second intention healing promotes cost-effective wound management that leads to superlative cosmetic results in carefully selected cases
When chosen in the appropriate clinical context, second intention wound healing can lead to excellent results and obviate the need for additional surgical reconstructive procedures
Summary
Second intention healing occurs when a surgical defect is allowed to heal by natural granulation and re-epithelialization rather than closed by a planned reconstructive technique. As granulation tissue forms and an open wound contracts, second intention healing promotes cost-effective wound management that leads to superlative cosmetic results in carefully selected cases. The following patient cases illustrate successful wound resolution by second intention following Mohs micrographic surgery in convex locations on the nose (Figure 1) and scalp (Figure 2).
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